much of this was cross posted from my medical blog.
the background of the covid epidemic is not just because it came from a lab leak, but that it was a bioengineered virus that was made to be more infectious and more lethal by doing gain of function research.
Gain-of-function research (GoF research or GoFR) is medical research that genetically alters an organism in a way that may enhance the biological functions of gene products. This may include an altered pathogenesis, transmissibility, or host range, i.e., the types of hosts that a microorganism can infect. This research is intended to reveal targets to better predict emerging infectious diseases and to develop vaccines and therapeutics.
and of course it can also be used to bioengineer bioweapons.
the gain of function scandal goes back years.
Here's why they were so desperate to cover up the lab leak:
— DataRepublican (small r) (@DataRepublican) July 29, 2026
The 2003 SARS outbreak exposed how outdated WHO's disease rules were, since the old International Health Regulations only covered a few named diseases. In response, the World Health Assembly launched a revision…
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Gain of function research was behind Covid...
GOF research had been outlawed by Obama but then he allowed it again a few weeks before Trump took office... and it has been outlawed on and off since then... an article last week said Trump outlawed it again, which I wondered about since he had outlawed it already.
But there are always holes and using money via NGOs... for example, the HHS stopped funding Ecohealth which was behind the covid funding leak, but an Ecohealth biolab proposed for the Philippines was not funded by HHS but the Dept of Defense (the Phil Govt refused so the grant has since expired).
Here is a long discussion of gain of function research and bird flu I wrote in 2024....if you thought Covid was bad, well, birdflu could be a lot worse... I apologize because I am not a good writer.
on my blog I was criticizing an LATImes article on bird flu that defended the need to do gain of function research. I will put the LAT in italics to separate it from my comments
Why scientists say we are fighting H5N1 bird flu with one hand tied behind our backs
By Susanne Rust and Karen Kaplan Dec. 24, 2024 3 AM PT
Gain-of-function research became controversial during the COVID-19 pandemic. But without it, “we’re just flying in the dark” when it comes to H5N1, said Felicia Goodrum, a molecular virologist at the University of Arizona....But when, where and how that could come to pass is hard to predict — in part, some researchers say, because of guardrails the federal government has placed around gain-of-function research.
I commented that bird flu is scary because of the high mortality in the few times it has spread to humans from birds (but no human to human transmission yet)... but as I point out, what is not known is how many people got it and never saw a doctor because they weren't sick enough to do so. CDC report on 71 human cases showed 2 deaths.
Many of the known bird flu deaths were in rural third world countries where people are in close contact with the free range chickens, or what I suspect was actually from what we in the Philippines call double dead meat, i.e. instead of killing sick animals, the owner sells them to local markets... (the protocol insists you kill and destroy infected chickens for this reason).
To some, the timing couldn’t be worse. At least 65 people in the U.S. have been infected with H5N1 since it arrived in North America in 2021, according to the Centers for Disease Control and Prevention 65 cases in four years. Got it. Most of the cases have involved workers on dairy and poultry farms, and their symptoms — including conjunctivitis and upper respiratory irritation — have tended to be mild. But in two cases, people have become severely ill, including a person in Louisiana and a teenager in Canada.
so two very sick people in four years but no deaths. Out of 65 cases in four years. But how many people got the disease and never sought medical care or were diagnosed?
well, anyway if you don't do such research you might not be able to develop a vaccine (China released Sinovax quite quickly because they knew the genome. How did the know the genome so fast? Duh).
Well as a doc, I worry about this because the paranoia over this scandal will result in people refusing known vaccines that have been around for decades and known to save lives, and people will die of these diseases.
Yes, I have seen children in Africa die of measles, whooping cough, tetanus. And my husband was old enough to remember smallpox when he worked in the southern Philippines.
all of these vaccines have a very low but real problem with side effects, mainly sore arm but also more serious problems like brain damage.
when the risk is low, lives are saved. And yes everything has a risk: I often pointed out to my patients that even driving their car to the clinic was risky.
Covid killed several of our neighbors who were young (elders die all the time so may not have had covid). But none of the various vaccines worked very good: Not the Sinovax, not the Sputnik, not tne AZ and not the mRNA vaccine.
Ironically, it was God who stopped the high death rate by having covid morph into the omicron varient that had a low death rate.
